An Investigational Drug Specifically for
Opioid-Induced Constipation

The investigational drug being evaluated in this clinical research study belongs to a class of drugs called opioid-receptor antagonists. The investigational drug is designed to target the underlying cause of constipation in people taking prescription pain medication (opioids) for chronic pain. Researchers are evaluating the investigational drug to see if it may potentially relieve constipation by increasing the frequency of bowel movements.

Constipation is one of the most common side effects for people managing chronic pain with a prescription pain medication. Because common treatments, including laxatives, do not provide relief for everyone, researchers are exploring potential new, future options, including this oral investigational drug.